Oleg V Tsodikov Selected Research

Kanamycin

11/2022	Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity.
1/2018	Potent 1,2,4-Triazino[5,6 b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis.
1/2016	Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis.
11/2013	Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis.
6/2012	Aminoglycoside multiacetylating activity of the enhanced intracellular survival protein from Mycobacterium smegmatis and its inhibition.
6/2011	Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB.

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Oleg V Tsodikov Research Topics

Disease

10	Tuberculosis (Tuberculoses) 01/2023 - 06/2012
8	Neoplasms (Cancer) 01/2023 - 02/2010
3	Infections 03/2023 - 01/2014
3	Ovarian Neoplasms (Ovarian Cancer) 01/2023 - 01/2021
3	Ewing Sarcoma (Sarcoma, Ewing) 01/2021 - 03/2016
3	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 12/2016 - 01/2012
2	Carcinogenesis 01/2021 - 01/2021
2	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 01/2016
2	Alzheimer Disease (Alzheimer's Disease) 12/2019 - 09/2015
2	Extensively Drug-Resistant Tuberculosis 01/2012 - 06/2011
1	Asthma (Bronchial Asthma) 01/2023
1	Neoplasm Metastasis (Metastasis) 01/2023
1	Brain Diseases (Brain Disorder) 12/2019
1	Bacterial Infections (Bacterial Infection) 08/2018
1	Hypercalcemia (Milk Alkali Syndrome) 03/2016
1	Lung Neoplasms (Lung Cancer) 03/2016
1	Leukemia 12/2015
1	Cross Infection (Nosocomial Infection) 02/2015
1	Colorectal Neoplasms (Colorectal Cancer) 07/2014
1	Starvation 01/2008

Drug/Important Bio-Agent (IBA)

8	Anti-Bacterial Agents (Antibiotics)IBA 03/2023 - 06/2011
8	AminoglycosidesIBA 01/2023 - 06/2011
7	Proteins (Proteins, Gene)FDA Link 11/2020 - 06/2012
6	Kanamycin FDA Link 11/2022 - 06/2011
5	Plicamycin FDA Link 01/2023 - 03/2016
5	AcetyltransferasesIBA 11/2022 - 06/2011
5	Transcription Factors (Transcription Factor)IBA 01/2021 - 12/2015
4	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 01/2014
3	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 02/2010
3	EnzymesIBA 10/2019 - 07/2013
2	PlatinumIBA 01/2023 - 01/2021
2	EWS-FLI fusion proteinIBA 11/2020 - 10/2016
2	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 02/2015 - 02/2013
1	SolutionsIBA 03/2023
1	endoplasmic reticulum glycoprotein p72IBA 01/2023
1	IsomerasesIBA 01/2023
1	Carboplatin (JM8)FDA LinkGeneric 01/2023
1	Sulfhydryl Compounds (Thiols)IBA 01/2023
1	zafirlukast (Accolate)FDA LinkGeneric 01/2023
1	Tumor Biomarkers (Tumor Markers)IBA 01/2023
1	Sp1 Transcription FactorIBA 01/2021
1	mithramycin AIBA 11/2020
1	Antineoplastic Agents (Antineoplastics)IBA 03/2016
1	prostate apoptosis response-4 proteinIBA 01/2016
1	Endoplasmic Reticulum Chaperone BiPIBA 01/2016
1	VimentinIBA 01/2016
1	glucose receptorIBA 01/2016
1	Nucleic AcidsIBA 12/2015
1	Methionine (L-Methionine)FDA Link 07/2014
1	Glycerophospholipids (Phosphoglycerides)IBA 07/2013
1	DNA Primase (Primase)IBA 02/2013
1	PyrophosphatasesIBA 02/2013
1	FluoroquinolonesIBA 01/2012
1	OxalatesIBA 01/2008
1	Radioactive Waste (Nuclear Waste)IBA 01/2008
1	formic acid (formate)IBA 01/2008
1	AcidsIBA 01/2008

Therapy/Procedure

8	Therapeutics 01/2023 - 09/2015